Effects of IFNγ administration on allograft rejection in ginbuna crucian carp
نویسندگان
چکیده
منابع مشابه
Effects of IFNγ administration on allograft rejection in ginbuna crucian carp.
In vertebrates, the rejection of allografts is primarily accomplished by cell-mediated immunity. We recently identified four IFNγ isoforms with antiviral activity in ginbuna crucian carp, Carassius auratus langsdorfii. However, involvement of the IFNγ isoforms in cell-mediated immunity, especially in T cell function remains unknown. Here we investigate expression of the IFNγ isoforms and effect...
متن کاملAdaptive immune response to Edwardsiella tarda infection in ginbuna crucian carp, Carassius auratus langsdorfii.
Edwardsiella tarda is an intracellular pathogen that causes edwardsiellosis in fish. Although cell-mediated immunity and innate immunity play a major role in protection against intracellular bacterial infection in mammals, their importance in protecting fish against E. tarda infection remain unclear. In this study, we examined cell-mediated and humoral immune responses in ginbuna crucian carp (...
متن کاملEffects of Anoxia on Serotonin Metabolism in Crucian Carp Brain
In the brain, oxygen is required for both the synthesis and the degradation of monoamine transmitters, so monoaminergic systems can be expected to be strongly affected by anoxia. However, crucian carp {Carassius carassius L.) may survive anoxia for many days or even weeks. In the present study, crucian carp were exposed to anoxia for 22, 76, and 160 h at 8°C. All survived and were found to excr...
متن کاملDisposition kinetics of orbifloxacin in tissues of crucian carp (Carassius auratus) following a single intramuscular administration
Background: Orbifloxacin is being widely used in China to treat fish infections in an extra-label manner, which may cause its potential residues in edible tissues. Aims: The purpose of this study was to determine the disposition kinetics of orbifloxacin in crucian carp (Carassius auratus) following intramuscular administration for its further safe appl...
متن کاملEffects of peritransplant administration of hematopoietic growth factors on the development of chronic allograft rejection.
CHRONIC allograft rejection (CR) remains as the major obstacle to successful organ transplantation. We have previously shown that persistence of donor multilineage hematolymphoid cells after transplantation correlates with the resistance to CR.13 We hypothesized in this study that perioperative administration of hematopoietic growth factors will be able to augment donor chimerism and therefore ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Developmental & Comparative Immunology
سال: 2016
ISSN: 0145-305X
DOI: 10.1016/j.dci.2016.04.021